Description
gp100 (aka Pmel17) is a 661 amino acid melanocyte glycoprotein that is overexpressed in melanomas. Several gp100-derived peptides have been identified as targets of cytotoxic T cells in melanoma patients. IGNYTE BIO offers T cells specific for gp100 209-217 (ITDQVPFSV) peptide in association with HLA-A2. These T cells were generated by multiple rounds of in vitro stimulations with the altered gp100 209-217 T210M (IMDQVPFSV) peptide