Antigen-Specific T Cells for Melanoma Research: Tyrosinase Our scientists were among the first to develop custom antigen-specific T cells for research use and have created them against a diverse range of targets, including viral, tumor, and self-antigens. We’re now developing the next generation of antigen-specific T cells to target some of today’s most prevalent and…
Antigen-Specific T Cells for Melanoma Research: MART-1 Our scientists were among the first to develop custom antigen-specific T cells for research use and have created them against a diverse range of targets, including viral, tumor, and self-antigens. We’re now developing the next generation of antigen-specific T cells to target some of today’s most prevalent and…
Irradiated PBMC as Research Tools Irradiated PBMC are PBMC from normal donors that have been subjected to high frequency ionizing X-Ray or gamma radiation. This exposure creates DNA damage that prevents certain cells (e.g., T cells, NK cells, B cells) from undergoing cell division. Irradiated PBMC components retain cellular functions, such as cytokine secretion, cytotoxicity,…
Donor-to-Donor Variation in Response to 3 Critical Recall Antigens Peripheral blood mononuclear cells (PBMC) are useful tools for evaluating immune response because they represent most of the resident immune cells in a donor’s sample, including T cells, B cells, natural killer (NK) cells, and monocytes. Varying Responses to Today’s Most Relevant Antigens In addition…
