Ponni has over 20 years of experience in biotechnology research and leadership. Her work in cell and gene therapy at Fred Hutchinson Cancer Research Center contributed to the launch of many successful immunotherapy companies.
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Neutrophils for Allergies and Inflammation Research Neutrophils are the most abundant leukocyte of peripheral blood and are known as the immune system’s first response to infection and injury. Recent studies have shown neutrophils’ effect in the regulation of both innate and adaptive immune response (A. Mocsai, 2013). Exposure to allergen leads to recruitment of…
FAQs on Using Dendritic Cells for Immuno-oncology and Autoimmunity Research and Development Dendritic cells are a family of immune cells that help to maintain balance in the immune system. The dendritic cell family is typically divided into four subgroups: Conventional dendritic cells (DC1 and DC2) Plasmacytoid dendritic cells Inflammatory dendritic cells Langerhans cells Dendritic cells…
Anti-HPV E7 T Cells and the Fight Against Cervical Cancer Cervical cancer induced by human papillomavirus (HPV) remains a global concern with high mortality rates, especially for women in under-developed and under-served portions of the world. According to the CDC, over 47,000 HPV-associated cancers occur in the United States each year, with women representing about…
Antigen-Specific T Cells for Melanoma Researchers: gp100 Our scientists were among the first to develop custom antigen-specific T cells for research use and have created them against a diverse range of targets, including viral, tumor, and self-antigens. We’re now developing the next generation of antigen-specific T cells to target some of today’s most prevalent and…
The Increasing Relevance of Tregs in Immunology and Oncology The study of regulatory T cells in autoimmunity, oncology, and infectious disease is still very much in its early days, though the applicable research findings are piling up. Recent studies have linked the importance of Tregs to key areas of immunology:1 Autoimmune Disease: Tregs have been…
Seasoned Life Sciences Team Launches Ignyte Bio To Speed Therapeutics Discovery Seattle biomaterials company specializes in human immune cell products and biopharma consulting services SEATTLE – (BUSINESS WIRE) –September 13, 2022 – Spurred by the pharmaceutical industry’s demand for immune cells for specialized therapeutic research, four biomaterials leaders have launched Ignyte Bio. The leadership team…
The Value of Donor Data Transparency in Biomaterial Sourcing In the spirit of open sharing and collaboration between scientists, we make all our donor data available to you as you’re selecting the best human immune cell products for your research. After all, we’re scientists, not salespeople. That means you don’t have to fill out a…