Anti-Tyrosinase CD8+ T Cells

$700.00

  • Product Size: ≥ 1M  
  • Catalog Number: TC-06   
  • Donor Number: 117   
  • Stock Left: 33
  • Lot Number: 01240423
  • C.of.A: link

33 in stock

Description

Tyrosinase is an enzyme expressed by normal melanocytes and melanoma cells. It catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. CD8+ T cells specific for the Tyrosinase (369-377, 371D) peptide: YMDGTMSQV, have been found in significant abundance in tumor-infiltrated lymph nodes from melanoma patients, suggesting their role in natural T cell response to melanoma. Ignyte Bio offers CD8+ T cells specific for the Tyrosinase (369-377, 371D) peptide: YMDGTMSQV in association with HLA-A*0201 protein.

Additional information

Donor #

117

Donor Age

56

Gender

F

Ethnicity

Caucasian

BMI

43.6

Donor Health

Normal

Smoker Status

N

Blood Type

O+

CMV Status

Neg

Fcgr3a-158 genotype

F/F

HLA-A

02:01, 02:01

HLA-B

15:01, 44:02

HLA-C

03:03, 05:01

HLA-DRB1

01:03, 04:04

HLA-DPA1

01:03, 01:03

HLA-DPB1

04:01, 04:01

HLA-DQA1

01:01, 03:01

HLA-DQB1

03:02, 05:01